Zika virus infection in a traveller returning to Europe from Brazil, March 2015.

Zika virus and congenital malformations in perspective.

Zika virus (ZIKV) has been on the agenda of virologists since many years already. Laboratories dealing with imported tropical diseases consider ZIKV infection among the differential diagnoses in cases of fever after travel to tropical Africa and Asia. The confirmation of autochthonous cases of this Old World flavivirus infection in Brazil in May 2015 was however surprising [1]. Already one mont...

False positive dengue NS1 antigen test in a traveller with an acute Zika virus infection imported into Switzerland.

We report the first case of an acute Zika virus infection imported into Switzerland by a traveller returning from Canoa Quebrada, Ceará state, in the north-eastern part of Brazil. Due to a false positive dengue virus NS1 antigen test, IgG antibody seroconversion and a suggestive clinical picture,an acute dengue fever was initially considered. However, because of lack of specific IgM-antibodies,...

Zika Virus Infection after Returning from Thailand

Zika virus infection in a traveller returning from the Maldives, June 2015.

We report a Zika virus (ZIKV) infection in a patient with fever and rash after returning to Finland from Maldives, June 2015. The patient had dengue virus (DENV) IgG and IgM antibodies but pan-flavivirus RT-PCR and subsequent sequencing showed presence of ZIKV RNA in urine. Recent association of ZIKV with microcephaly highlights the need for laboratory differentiation of ZIKV from DENV infectio...

Zika Virus Infection in Australia following a Monkey Bite in Indonesia.

A traveller returning to Australia developed Zika virus infection, with fever, rash and conjunctivitis, with onset five days after a monkey bite in Bali, Indonesia. Flavivirus RNA detected on PCR from a nasopharyngeal swab was sequenced and identified as Zika virus. Although mosquito-borne transmission is also possible, we propose the bite as a plausible route of transmission. The literature fo...